The association between weight change, cognitive, functional, and behavioral

 
   Lead Investigator:    Tzeyu Michaud
   Institution      :    University of Nebraska Medical Center
   E-Mail           :    tzeyu.michaud@unmc.edu
   Proposal ID      :    855


   Publications:


1  Michaud TL, Siahpush M, Farazi PA, Kim J, Yu F, Su D, Murman DL
   The Association between Body Mass Index, and Cognitive, Functional, and Behavioral Declines for Incident Dementia
   Journal Article  J Alzheimers Dis,4:1507-1517,2018,PMC6441968

   PUBLISHED





   Proposal Description:
   We seek to evaluate whether the baseline BMI and weight change over time are associated with the clinical progression before, and on and after the onset of dementia. The clinical progression of dementia is defined by its clinical features: cognition (MMSE, and CDR-SB)), function (FAQ), and Behavior (NPI-Q). That is, we will evaluate the weight change on the change of the MMSE (CDR-SB) score, the FAQ scores, and the NPI-Q score, respectively, using separate generalized linear mixed effect models.